![]() SneakPeek gender test is the earliest and most accurate method for fetal sex determination. No false positive or false negative results were observed in this study.Ĭonclusion: SneakPeek® Early Gender Test was shown to be 100% accurate for fetal sex determination at 6 weeks gestation. SneakPeek accuracy, sensitivity, and specificity were 100%, 100%, and 100% for fetal sex identification, respectively. All sonogram results matched the SneakPeek test results in this study. Test results at later gestational ages (7 and 8+weeks) matched the six-week test results. Results: SneakPeek accurately determined fetal sex at six weeks for 113 subjects in this study, results for two subjects were inconclusive. Sonography was also used to confirm SneakPeek test results for 103 pregnancies in the study. Since the SneakPeek® Early Gender Test was found to be 99.9% accurate at 7-weeks’ and 8-weeks’ gestation or later, the fetal sex test results for six-week gestation samples were confirmed with the 7-week and 8-week to 10-week sample results. Fetal sex was determined from the qPCR results using an algorithm that includes theQuantification Cycle (Cq) values of the Y-target sequence and autosomal control gene. ![]() Real-time quantitative PCR was utilized to detect male fetal DNA using a multi-copy sequence on the Y chromosome and total cell-free DNA using an autosomal control target gene. Using a commercial DNA isolation kit, circulating cell-free DNA (ccfDNA) was extracted from the maternal plasma samples. Maternal plasma was separated from whole blood via centrifugation. Three to four milliliters (mL) of maternal blood were drawn from each participant via venipuncture at three gestational ages (i.e., 6, 7, and 8 -10 weeks’ gestation). After excluding participants that reported miscarriage during the study, reported twin/triplet pregnancy, or miscalculated gestational age at the time of the initialsample collection, 115 individuals completed the trial in its entirety. Method: Between May and September 2021, 156 pregnant women were recruited from 12 clinics in the United States. The SneakPeek assay was further optimized to enable fetal sex identification at earlier gestations and its performance characteristics were determined at 6-weeks’ gestation. To our knowledge, no prior study has shown fetal sex identification from maternal plasma earlier than seven weeks of gestation with high accuracy. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Ĭlinics Mother Child Health, Vol.19 Iss.4 No:1000419 ABSTRACTīackground: The SneakPeek® Early Gender Test was previously shown to be 99.9% accurate in determining fetal sex as early as seven weeks of gestation. ![]() CMCH-22-17127 (R) Published: 0, DOI: 10.35248/2090-7214.22.19.419Ĭitation: Szucs HD, Asprer L, Abunadi N, Milot H, Cacia S, Jacob C (2022)SneakPeek Early Gender Test: The Earliest and Most Accurate Method for Fetal Sex Determination at 6-Weeks Gestation. CMCH-22-17127 Editor assigned: 1, PreQC No. Gateway Genomics, San Diego, California, USAĬorrespondence to: Henriett Diana Szucs, Gateway Genomics, San Diego, California, US, E-mail: 0, Manuscript No. The SneakPeek “Fast Track” test will have your result the next day.Henriett Diana Szucs*, Lia Asprer, Nora Abunadi, Haley Milot, Sarah Cacia, Chris Jacob The standard SneakPeek test will have your result in two days. For fraternal twins, finding male DNA means at least one baby is a boy, but cannot distinguish if the second is a boy or girl. If no male DNA is found, then both babies are girls. In the case of identical twins, if male DNA is found, then both babies are boys. SneakPeek looks for male DNA in the fetal DNA found in mom's blood sample. Can SneakPeek determine the gender of each one? To avoid inaccurate test results, it's imperative to wait until you're 8 weeks pregnant to ensure the level of Y chromosomes is high enough to read. SneakPeek looks for Y chromosomes in the fetal DNA found in mom's blood. 2017 4:358).Ĭan I t ake a SneakPeek Test b efore I’m 8 w eeks p regnant ? See the peer-reviewed study in the Journal of Pregnancy and Child Health. In a separate laboratory test, fetal sex was accurately determined in 99.6% of 241 pregnant women at 9 weeks gestational age and later into pregnancy. See the peer-reviewed study in the International Journal of Pregnancy and Childbirth (Int J Pregn & Chi Birth. In laboratory testing, SneakPeek accurately determined fetal sex in 99.1% of 108 pregnant women at 8 weeks gestational age.
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